2026

Targeting immune cells in the aged brain reveals that engineered cytokine IL-10 enhances neurogenesis and improves cognition

P. Navarro Negredo; J. You; M. Hauptschein; A. B. Schroer; D. J. Richard et al.

Immunity. 2026. Vol. 59, num. 2, p. 458 – 476.e13. DOI : 10.1016/j.immuni.2026.01.016.

Detailed record

View at publisher

2025

Spatial transcriptomic clocks reveal cell proximity effects in brain ageing

E. D. Sun; O. Y. Zhou; M. Hauptschein; N. Rappoport; L. Xu et al.

Nature. 2025. Vol. 638, num. 8049, p. 160 – 171. DOI : 10.1038/s41586-024-08334-8.

Detailed record

View at publisher

2024

Spatiotemporal transcriptomic profiling and modeling of mouse brain at single-cell resolution reveals cell proximity effects of aging and rejuvenation

E. D. Sun; O. Y. Zhou; M. Hauptschein; N. Rappoport; L. Xu et al.

2024

Detailed record

View at publisher

Identification of protein aggregates in the aging vertebrate brain with prion-like and phase-separation properties

I. Harel; Y. R. Chen; I. Ziv; P. P. Singh; D. Heinzer et al.

Cell reports. 2024. Vol. 43, num. 6. DOI : 10.1016/j.celrep.2023.112787.

Detailed record

View at publisher

TISSUE: uncertainty-calibrated prediction of single-cell spatial transcriptomics improves downstream analyses

E. D. Sun; R. Ma; P. Navarro Negredo; A. Brunet; J. Zou

Nature methods. 2024. Vol. 21, num. 3, p. 444 – 454. DOI : 10.1038/s41592-024-02184-y.

Detailed record

View at publisher

2023

Chromatin accessibility dynamics of neurogenic niche cells reveal defects in neural stem cell adhesion and migration during aging

R. W. Yeo; O. Y. Zhou; B. L. Zhong; E. D. Sun; P. Navarro Negredo et al.

Nature Aging. 2023. Vol. 3, num. 7, p. 866 – 893. DOI : 10.1038/s43587-023-00449-3.

Detailed record

View at publisher

2021

Unwanted help from T cells in the aging central nervous system

P. Navarro Negredo; A. Brunet

Nature Aging. 2021. Vol. 1, num. 4, p. 330 – 331. DOI : 10.1038/s43587-021-00053-3.

Detailed record

View at publisher

2020

Aging and Rejuvenation of Neural Stem Cells and Their Niches

P. Navarro Negredo; R. W. Yeo; A. Brunet

Cell Stem Cell. 2020. Vol. 27, num. 2, p. 202 – 223. DOI : 10.1016/j.stem.2020.07.002.

Detailed record

View at publisher

2019

Single-cell analysis reveals T cell infiltration in old neurogenic niches

B. W. Dulken; M. T. Buckley; P. Navarro Negredo; N. Saligrama; R. Cayrol et al.

Nature. 2019. Vol. 571, num. 7764, p. 205 – 210. DOI : 10.1038/s41586-019-1362-5.

Detailed record

View at publisher

2018

The WDR11 complex facilitates the tethering of AP-1-derived vesicles

P. Navarro Negredo; J. R. Edgar; P. T. Manna; R. Antrobus; M. S. Robinson

Nature communications. 2018. Vol. 9, num. 1. DOI : 10.1038/s41467-018-02919-4.

Detailed record

View at publisher

2017

Contribution of the clathrin adaptor AP-1 subunit µ1 to acidic cluster protein sorting

P. Navarro Negredo; J. R. Edgar; A. G. Wrobel; N. R. Zaccai; R. Antrobus et al.

Journal of Cell Biology (JCB). 2017. Vol. 216, num. 9, p. 2927 – 2943. DOI : 10.1083/jcb.201602058.

Detailed record

View at publisher

2012

Tensor-Based Morphometry and Stereology Reveal Brain Pathology in the Complexin1 Knockout Mouse

C. Kielar; S. J. Sawiak; P. Navarro Negredo; D. H. Y. Tse; A. J. Morton

PLoS ONE. 2012. Vol. 7, num. 2. DOI : 10.1371/journal.pone.0032636.

Detailed record

View at publisher