Giorgi-Cavaglieri Chair in Immunology of the Aging Brain

Illustration by Ximena Fernandez Castro

Research Projects

Target inflammation for brain resilience

Use protein engineering to specifically target immune cells and pathways in the old brain to improve brain function at the cellular, circuit and behavioral levels

Find age-related antigens in old organs

Use antigen screening and T cell receptor sequences to determine what attracts T cells to aged organs

Role of immune cells in rejuvenation

Establish the role of immune cells in rejuvenating interventions, is T cell rejuvenation necessary or sufficient to bring beneficial effects?