To translate the preliminary findings of MEDUSA into a versatile technology, two directions will be explored: [1] analysis of the structure / function relation of aptamer modification toward selectivity; [2] transformation of the backbone to generate sensitive molecular diagnostic sensors. Together, this project promises to redefine the current golden standard of molecular affinity evolution for multivalent targets and establishes a new common-practice in ligand identification.
- Field: Nanotechnology, Ligand discocery
- Laboratory: Programmable Biomaterials Laboratory (STI IMX PBL)
- Project leader: Maartje M.C. Bastings
- Budget: 30’000.00 CHF