Westmann Lab of Systems and Synthetic Evolutionary Biology

Abstraction of adaptive landscapes of bacterial systems

We study how living systems encode and process information through gene regulation. By combining synthetic biology, high-throughput experiments, and computational analysis, our lab builds quantitative sequence–function maps to uncover the principles governing regulatory specificity and functional variation. We use these insights to understand how regulatory systems work and evolve, and to guide the design of new biological parts and systems.