2024
Reviews
Mechanisms and functions of protein S-acylation
Nature Reviews Molecular Cell Biology. 2024-02-14. DOI : 10.1038/s41580-024-00700-8.Theses
S-acylation and lipid exchange at the ER-Golgi membrane contact sites regulate pathogen entry in human cells
Lausanne, EPFL, 2024.2023
Journal Articles
S-acylation: an orchestrator of the life cycle and function of membrane proteins
Febs Journal. 2023-10-16. Vol. 291, num. 1, p. 45-56. DOI : 10.1111/febs.16972.SARS-CoV-2 hijacks a cell damage response, which induces transcription of a more efficient Spike S-acyltransferase
Nature Communications. 2023. Vol. 14, num. 7302. DOI : 10.1038/s41467-023-43027-2.Dynamics of CLIMP-63 S-acylation control ER morphology
Nature Communications. 2023-01-17. Vol. 14, num. 1. DOI : 10.1038/s41467-023-35921-6.Conference Papers
ER-Golgi membrane contact sites control the formation of plasma membrane lipid nanodomains
2023-02-01. Annual Meeting of the American-Society-for-Cell-Biology/ European-Molecular-Biology-Organisation (ASCB/EMBO), Washington, DC, DEC 03-07, 2022. p. 274-274.Reviews
Refining S-acylation: Structure, regulation, dynamics, and therapeutic implications
Journal Of Cell Biology. 2023-09-27. Vol. 222, num. 11, p. e202307103. DOI : 10.1083/jcb.202307103.Theses
Characterization of Cyclo His-Pro for the prevention and treatment of liver disease and muscular dystrophy
Lausanne, EPFL, 2023.Patents
Inhibitors of acyl protein thioesterases against microbial infections
WO2023139248.
2023.2022
Journal Articles
ER-Golgi-localized proteins TMED2 and TMED10 control the formation of plasma membrane lipid nanodomains
Developmental Cell. 2022-10-10. Vol. 57, num. 19. DOI : 10.1016/j.devcel.2022.09.004.Local and substrate-specific S-palmitoylation determines subcellular localization of G alpha o
Nature Communications. 2022-04-19. Vol. 13, num. 1, p. 2072. DOI : 10.1038/s41467-022-29685-8.2021
Journal Articles
S-acylation by ZDHHC20 targets ORAI1 channels to lipid rafts for efficient Ca2+ signaling by Jurkat T cell receptors at the immune synapse
Elife. 2021-12-16. Vol. 10, p. e72051. DOI : 10.7554/eLife.72051.S-acylation controls SARS-CoV-2 membrane lipid organization and enhances infectivity
Developmental Cell. 2021-10-25. Vol. 56, num. 20, p. 2790-+. DOI : 10.1016/j.devcel.2021.09.016.Palmitoylated acyl protein thioesterase APT2 deforms membranes to extract substrate acyl chains
Nature Chemical Biology. 2021-04-01. Vol. 17, num. 4, p. 438-U173. DOI : 10.1038/s41589-021-00753-2.Akt Is S-Palmitoylated: A New Layer of Regulation for Akt
Frontiers In Cell And Developmental Biology. 2021-02-15. Vol. 9, p. 626404. DOI : 10.3389/fcell.2021.626404.Conference Papers
ANTXR2 as a novel player in skeletal muscle stem cells
2021-10-01.Reviews
Harnessing the Membrane Translocation Properties of AB Toxins for Therapeutic Applications
Toxins. 2021-01-06. Vol. 13, num. 1, p. 36. DOI : 10.3390/toxins13010036.2020
Journal Articles
A toxic palmitoylation of Cdc42 enhances NF-kappa B signaling and drives a severe autoinflammatory syndrome
Journal Of Allergy And Clinical Immunology. 2020-11-01. Vol. 146, num. 5, p. 1201-1204.e8. DOI : 10.1016/j.jaci.2020.03.020.Wnt-controlled sphingolipids modulate Anthrax Toxin Receptor palmitoylation to regulate oriented mitosis in zebrafish
Nature Communications. 2020-07-03. Vol. 11, num. 1, p. 3317. DOI : 10.1038/s41467-020-17196-3.Ligand Binding to the Collagen VI Receptor Triggers a Talin-to-RhoA Switch that Regulates Receptor Endocytosis
Developmental Cell. 2020-05-18. Vol. 53, num. 4, p. 418-+. DOI : 10.1016/j.devcel.2020.04.015.Hemagglutinin of Influenza A, but not of Influenza B and C viruses is acylated by ZDHHC2, 8, 15 and 20
Biochemical Journal. 2020-01-01. Vol. 477, p. 285-303. DOI : 10.1042/BCJ20190752.Reviews
Mammalian membrane trafficking as seen through the lens of bacterial toxins
Cellular Microbiology. 2020-04-01. Vol. 22, num. 4, p. e13167. DOI : 10.1111/cmi.13167.Theses
Mapping and Analysis of the Complexity of Lipid Metabolism for Applications in Health and Sustainability
Lausanne, EPFL, 2020.Patents
Use of deoxysphingolipids as anti-toxins and anti-virals
WO2020074465; EP3636255.
2020.