My primary research interests are in studying antibody responses induced by Capsids derived from endogenous retroviral elements, such as the members of the PNMA2 family, and their role in autoimmune disorders.
My research aims to develop novel antivenom therapies for snake bite envenoming to overcome the limitations of current polyclonal antibody-based treatments. By focusing on toxins from Echis ocellatus, we aim to map the interactions between venom and antivenom using cryoEMPEM and correlate epitope specificity with neutralization and cross-reactivity.
My research explores antibody-mediated immunity to vector-borne RNA viruses, such as Dengue, Yellow Fever, and Chikungunya. Using a structure-guided approach, I aim to contribute to the design of engineered immunogens that could serve as vaccine candidates against these global health threats.
My project investigates the antibody response to enteroviral infections at local and systemic levels. By complexing enteroviruses with antibodies isolated from patient samples, I aim to map viral epitopes using cryo-electron microscopy. This insight will guide the design of novel immunogens with tailored immunogenicity, making it a potential strategy towards vaccine design.
