| ACOUA | Academic Output Archive | EPFL |
| AREC | Animal Research Ethics Committee | EPFL |
| c4science | Code for Science | EPFL |
| DPO | Data Protection Officer | EPFL |
| DSI | (former VPSI) Domaine des Systèmes d’Information (Information Systems Management Department) | EPFL |
| HREC | Human Research Ethics Committee | EPFL |
| OSSC | Open Science Strategic Committee | EPFL |
| RCP | Research Computing Platform | EPFL |
| REO | Research Office | EPFL |
| SDSC | Swiss Data Science Center | EPFL |
| SCITAS | Scientific IT and Application Support | EPFL |
| SISB | (i.e. Library) Scientific information and libraries (Information scientifique et bibliothèques) | EPFL |
| TTO | Technology Transfer Office | EPFL |
| ACS | American Chemical Society | |
| API | Application Programming Interface | |
| ARK | Archival Resource Key | |
| CC | Creative Commons | |
| CSCS | Swiss National Supercomputing Centre | |
| CYD | Cyber Defense | |
| DCC | Digital Curation Centre | |
| DDI | Data Documentation Initiative | |
| DLCM | Digital Lifecycle Management | |
| DMP | Data Management Plan | |
| DOI | Digital Object Identifier | |
| DP | Data Protection | |
| ELN | Electronic Lab Notebook | |
| EOSC | European Open Science Cloud | |
| ERC | European Research Council (Funding agency) | |
| FADP | Federal Act on Data Protection | |
| FAIR | Findable, Accessible, Interoperable, and Reusable | |
| FORCE11 | Future of Research Communications and e-Scholarship | |
| GDPR | General Data Protection Regulation | |
| GIT | Global Information Tracker | |
| GPL | GNU Public License | |
| HANDLE | (Prefix registration system) | |
| HRA | Human Research Act | |
| I/O | Input Output | |
| IPR | Intellectual Property Rights | |
| ISO | International Standard Organization | |
| IT | Information Technologies | |
| LIMS | Laboratory Information Management System | |
| NAS | Network Attached Storage | |
| NCCR | National Centres of Competence in Research | |
| OA | Open Access | |
| OAIS | Open Archival Information System | |
| OECD | Organization for Economic Co-operation and Development | |
| ORCID | Open Researcher and Contributor ID | |
| ORD | Open Research Data | |
| PID | Persistent Identifier | |
| PPDP | Privacy Preserving Data Publishing | |
| RDA | Research Data Alliance | |
| Re3data | Registry of Research Data Repositories | |
| RDM | Research Data Management | |
| SDK | Software Development Kit | |
| SDMS | Scientific Data Management System | |
| SNSF | Swiss National Science Foundation (Funding agency) | |
| URL | Uniform Resource Locator | |
| URN | Universal Resource Name | |
| UX | User Experience | |