Publications

Highlights

Morphology, physiology and synaptic connectivity of local interneurons in the mouse somatosensory thalamus
« Morphology, physiology and synaptic connectivity of local interneurons in the mouse somatosensory thalamus », Jane Simko and Henry Markram, The Journal of Physiology, November 2021

2026

An interpretable deep learning framework for classifying neuronal morphologies using topology and graph neural networks

L. Kanari; S. Schmidt; F. Casalegno; É. Delattre; J. B. Lukic et al. 

Scientific Reports. 2026. DOI : 10.1038/s41598-026-71217-7.

Multimodal single-cell dataset of juvenile rat neocortical interneurons—Morphology, whole-cell patch electrophysiology and histological slices

M. Toledo-Rodriguez; Y. Shi; J. Meystre; D. La Mendola; R. Ranjan et al. 

Frontiers in Neuroscience. 2026. Vol. 20. DOI : 10.3389/fnins.2026.1926661.

Temperature dependence of HCN channel kinetics: A systematic comparison across mammalian isoforms and species

R. Ranjan; E. Logette; M. Herzog; V. Büchillier; E. Scantamburlo et al. 

Experimental Physiology. 2026. DOI : 10.1113/ep093939.

Do we understand orientation selectivity? A simulation study

H. T. Dictus; A. Arnaudon; D. Mandge; J. Herttauinen; H. Markram et al. 

2026

eFEL: Electrophysiology Feature Extraction Library

D. Mandge; M. A. Tuncel; A. T. Jaquier; I. Kilic; T. Damart et al. 

Bioinformatics. 2026.  p. btag328. DOI : 10.1093/bioinformatics/btag328.

Sex-specific systemic and brain metabolic responses to a standardized ketogenic diet in mice

C. Lorin; G. Diaceri; M. Garcia; E. Logette; H. Markram et al. 

Lab Animal. 2026. DOI : 10.1038/s41684-026-01732-7.

A multimodal spatial atlas of transcriptomic, morphological, and electrophysiological cell type densities in the mouse brain

C. Verasztó; Y. Roussel; L. Kanari; S. Piluso; H. Markram et al. 

PLOS Computational Biology. 2026. Vol. 22, num. 3. DOI : 10.1371/journal.pcbi.1014106.

Uncovering the Basis of Human Connectome Complexity: The Role of Neuronal Morphology

N. Barros Zulaica; D. Egas Santander; L. Kanari; Y. Shi; R. Perin et al. 

2026

A Detailed Model for Understanding the Human Neocortex

N. B. Zulaica; L. Kanari; V. Sood; P. Rai; A. Arnaudon et al. 

2026

An interactive 3D atlas of gene expression in the mouse brain

H. Carey; S. Piluso; I. Bjerke; X. Gui; S. Yates et al. 

2026

Modeling and simulation of neocortical micro- and mesocircuitry (Part II, Physiology and experimentation)

J. B. Isbister; A. Ecker; C. Pokorny; S. Bolaños-Puchet; D. Egas Santander et al. 

eLife. 2026. Vol. 13. DOI : 10.7554/elife.99693.3.

Modeling and simulation of neocortical micro- and mesocircuitry (Part I, anatomy)

M. W. Reimann; S. Bolaños-Puchet; J-D. Courcol; D. Egas Santander; A. Arnaudon et al. 

eLife. 2026. Vol. 13. DOI : 10.7554/elife.99688.3.

Simulation of the mouse visual cortex

H. T. Dictus / H. Markram (Dir.)  

Lausanne, EPFL, 2026. 

Investigating the Thalamic Reticular Nucleus: A Multi-Scale Computational Approach from Cellular Diversity to Network Function

P. Litvak / S. L. Hill; A. Romani (Dir.)  

Lausanne, EPFL, 2026. 

2025

Higher-order interactions in neuronal function: From genes to ionic currents in biophysical models

M. Reva; A. Arnaudon; M. Zbili; A. Makkeh; H. Markram et al. 

Proceedings of the National Academy of Sciences. 2025. Vol. 122, num. 40. DOI : 10.1073/pnas.2500048122.

Biophysical modeling of thalamic reticular nucleus subpopulations and their differential contribution to spindle dynamics

P. Litvak; N. D. Hartley; R. Kast; G. Feng; Z. Fu et al. 

iScience. 2025. Vol. 28, num. 9, p. 113393. DOI : 10.1016/j.isci.2025.113393.

N-glycosylation modulates the inactivation kinetics of the Kv3.4 ion channel

R. Ranjan; E. Logette; M. Herzog; V. Buchillier; E. Scantamburlo et al. 

iScience. 2025. Vol. 28, num. 9, p. 113409. DOI : 10.1016/j.isci.2025.113409.

Of mice and men: Dendritic architecture differentiates human from mouse neuronal networks

L. Kanari; Y. Shi; A. Arnaudon; N. Barros-Zulaica; R. Benavides-Piccione et al. 

iScience. 2025. Vol. 28, num. 7, p. 112928. DOI : 10.1016/j.isci.2025.112928.

A multiscale electro-metabolic model of a rat neocortical circuit reveals the impact of ageing on central cortical layers

S. Farina; A. Cattabiani; D. Mandge; P. Shichkova; J. B. Isbister et al. 

PLOS Computational Biology. 2025. Vol. 21, num. 5. DOI : 10.1371/journal.pcbi.1013070.

Seizure and redox rescue in a model of glucose transport deficiency

J. S. Coggan; P. Shichkova; H. Markram; D. Keller 

PLoS Computational Biology. 2025. Vol. 21, num. 4, p. e1012959. DOI : 10.1371/journal.pcbi.1012959.