Project Proposals
Les projets de thèse de maîtrise disponibles tournent autour de l’adaptation environnementale des communautés microbiennes à l’échelle de la population et moléculaire. L’objectif principal est de déterminer la tolérance de l’écosystème et le potentiel d’adaptation au réchauffement, ainsi que d’identifier les espèces clés qui impactent la robustesse et la résilience des microbiomes de la cryosphère.
Bioinformatics based project:
Composition and function of crysphere microbiomes
This project will involve analysing in-house and publicly available metagenomes to determine their taxonomic compositions and functions and identify global genomic features of cryo-microbiomes. This would be followed up with a meta-annalysis to determine trends, patterns, and emergent qualities of microbiomes across different cryosphere environments.
Laboratory based project:
Molecular adaptation strategies of alpine snow microorganisms to warming
This project will involve isolation of alpine snow microbial members, followed by genomic analysis to determine their metabolic potential in cold and warming adaptation. This will be complemented with cultivation if isolates at a gradient of temperatures and isolation of their RNA/proteins to determine the molecular changes triggered by changes in temperature. This work will be used to asses the thermal tolerances of cryospheric microorganisms. This project will also include an bioinformatic and analysis component, but will heavily rely on initial lab-work. Depending on the preference of the student, there is also an option to incorporate filed work into the project.
Completed Master Projects
2023
Microfluidic device for specific detection of pathogens
Mattia Lazzaroni
In conjunction with bNovate Technologies SA