Laboratory of Nanoscale Biology (LBEN)
LBEN develops novel imaging methods, and computational tools to advance our understanding of biology and physical chemistry. Biological problems include clustering of membrane proteins, protein aggregation, microbiome composition. We are also interested in the phenomena occurring at the water-2d material interfaces. Nanoscale imaging (TEM optical nanoscopy) is a crucial component for the development and application of two types of nanoscale sensors : a) Nanopores used for single molecule characterization. b) Color centers in diamond or hexagonal boron nitride used for nanoscale mapping of physical quantities such as temperature, pH, electromagnetic field, ion concentration.
Access to website
Super-resolution, quantitive imaging, optics, electron microscopy, single-molecule
- A. Descloux, K.S. Grußmayer, A. Radenovic. “Parameter-free image resolution estimation based on decorrelation analysis,” Nature Methods 2019 to appear
- J.D. Feng, H. Deschout, S. Caneva, S. Hofmann, I. Loncaric, P. Lazic, A. Radenovic, “Imaging of Optically Active Defects with Nanometer Resolution,” Nano Letters, vol. 18, no. 3, pp. 1739-1744, February 2018.
- H. Deschout, T. Lukes, A. Sharipov, D. Szlag, L. Feletti, W. Vandenberg, P. Dedecker, J. Hofkens, M. Leutenegger, T. Lasser, A. Radenovic, “Complementarity of PALM and SOFI for super-resolution live cell imaging of focal adhesions,” Nature Communications, vol. 7, no. 13693, December 2016.
- P. Annibale, S. Vanni, M. Scarselli, U. Rothlisberger, A. Radenovic, “Quantitative Photo Activated Localization Microscopy: Unraveling the Effects of Photoblinking,” Plos One, 6(7), July 2011.
P. Annibale, S. Vanni, M. Scarselli, U. Rothlisberger, A. Radenovic, “Identification of clustering artifacts in photoactivated localization microscopy,” Nature Methods, 8(7), pp. 527-528, June 2011.