AGORA Workshop

Spatial resolved transcriptomics and multiplexing of antibodies aim to detect mRNAs or/and proteins of a single cell in the context of tissue environment. This spatial context is crucial for understanding key mechanisms in cell biology, neurobiology or tumor biology like cell-cell interactions. Many technologies based on different methods (microdissection, in situ hybridization, in situ sequencing, in situ capturing and cyclic immunodetection) have been developed to fulfill this need. In general, those procedures are still under development, difficult to implement in a lab or come with high investment.

The proposed workshop is a great opportunity to advance your knowledge about the existing technologies, your network and discuss with the industry.

9:00 – 9:20 – Welcome and registration

9:20 – 9:30 – Introduction

9:30 – 10:45 – Plenary session

Uncovering the spatial landscape of development from
transcriptomics to lipidomics, Prof. Gioele LaManno (EPFL, Switzerland)

Dr. Roser Vento-Tormo (WSI Cambridge, UK)

Spatial Multi-Omics Sequencing, Prof. Rong Fan (Yale, USA)

10:45 – 11:15 – Poster session and coffee break

11:15 – 12:00 – Flash talks selected

12:00 – 13:30 – Standing lunch and poster session

13:30 – 14:15 – Plenary session

Highly multiplexed tissue imaging for precision
medicine applications, Prof. Bernd Bodenmiller (UNIZH, Switzerland)

The Evolution of Spatial Biology from the perspective of a core
facility director, Prof. Jared K. Burks (MD Anderson Cancer Center, USA)

14:15 – 15:45 – Breakout sessions

Applications in research: Which technologies for my research projects? Chair: Dr. Arne Seitz and Dr. Denarda Dangaj

Diagnostic: How to apply spatial-omics in human medical diagnostic?  Chair: Prof. Inti Zlobec and Prof. Olivier Michelin

Data analysis and integration: How to interpret and integrate data from multi-omics procedures? Chair: Prof. Raphaël Gottardo

15:45 – 16:15 – Poster session and coffee break

16:15 – 16:30 – Short recap of breakout sessions

16:30 – 17:15 – Plenary session (2 x 20 min talks + 5min questions)

3D molecular reconstruction of tumors, Prof. Nikolaus Rajewsky (MDC Berlin, Germany)

Integrated spatial and single-cell transcriptomics identifies
tumor-stroma interactions governing skin cancer progression
and resistance to therapy, Dr. François Kuonen (CHUV, Switzerland)

17:15 – 19:00 – Aperitif, Poster session and POSTER AWARDS.

Dr. Jessica Sordet-Dessimoz, EPFL, Lausanne

Dr. Stéphanie Tissot, CTE, CHUV and LICR, Lausanne

Prof. Johanna Joyce, UNIL and LICR, Lausanne

Prof. Susan Gasser, ISREC Foundation, Lausanne