MEYLAN Lab

In our research laboratory, we study the mechanisms that govern the development of lung cancer. To this end, we use a combination of bioinformatics analyses, cancer-derived mouse and human cell lines, tumor tissue material and genetically-engineered mouse models of human lung cancer. We focus on cellular signaling events that impact tumor cells, the immune system and tumor metabolism. Because immune and metabolic alterations could influence tumor development profoundly, understanding these crucial perturbations of tumors may lead to new perspectives of treatment.

Congratulations Svenja, for your research paper

21.08.18 – Our paper entitled “Snail mediates repression of the Dlk1-Dio3 locus in lung tumor – infiltrating immune cells” was published in Oncotarget.

Congratulations for our review on glucose transporters in cancer
15.06.18 –Congratulations, Pierre-Benoit, Caroline and Etienne, for the review on GLUTs in cancer.

13.12.17 – Congratulations for the publication of our research article!

Our paper “RANKL signaling sustains primary tumor growth in genetically engineered mouse models of lung adenocarcinoma” is published in the Journal of Thoracic Oncology.

13.12.17 – Congratulations to the two co-first authors, Julien and Svenja, for a fantastic collaborative effort.

Our paper “Neutrophils and Snail Orchestrate the Establishment of a Pro-tumor Microenvironment in Lung Cancer” has been published at Cell Reports.

Tumor metabolism helps classify hepatoblastoma

21.09.17 – EPFL scientists have identified new biomarkers that could help more accurately classify the two main subtypes of hepatoblastoma, a liver cancer in children. The study is published at EMBO Molecular Medicine.

Congratulations to Jawahar for his paper

02.06.17 – Celebration of our paper “RIP4 inhibits STAT3 signaling to sustain lung adenocarcinoma differentiation”, published at Cell Death & Differentiation.

The SV Section Teaching Prize to Prof. Etienne Meylan

10.10.16 – Congratulations to Prof. Etienne Meylan for the 2016 SV Teaching Prize !

Congratulations!

11.08.16 – Jawahar Kopparam, PhD (14.07.2016) Read the whole article

Congratulations!

05.07.16 – Mark Masin, PhD (18.12.2015) Read the whole article

Cancer: Tumors Absorb Sugar for Mobility

30.07.14 – Some cancer cells are characterized by both high sugar intake and high mobility. Researchers at EPFL show that these two phenomena are related. The study is published at Cancer & Metabolism.

Eight professors appointed at EPFL

07.12.12 – At its meeting held in December, the Board of the Swiss Federal Institutes of Technology appointed eight professors at EPFL.

A warm welcome to two new SV faculty members!

11.04.11 – Two UNIL young professors joining the EPFL School of Life Sciences… Read the whole article