Microfluidics as an Enabling Technology for Personalized Cancer Therapy.
Mathur L, Ballinger M, Utharala R, Merten CA.
Small. 2019 Nov 20:e1904321. doi: 10.1002/smll.201904321. [Epub ahead of print] Review.PMID: 31747127
Microfluidics as an Emerging Precision Tool in Developmental Biology.
Sonnen KF, Merten CA.
Dev Cell. 2019 Feb 11;48(3):293-311. doi: 10.1016/j.devcel.2019.01.015. Review.PMID: 30753835
A microfluidics platform for combinatorial drug screening on cancer biopsies.
Eduati F, Utharala R, Madhavan D, Neumann UP, Longerich T, Cramer T, Saez-Rodriguez J, Merten CA.
Nat Commun. 2018 Jun 22;9(1):2434. doi: 10.1038/s41467-018-04919-w.PMID: 29934552 Free PMC Article
A Versatile, Low-Cost, Multiway Microfluidic Sorter for Droplets, Cells, and Embryos.
Utharala R, Tseng Q, Furlong EEM, Merten CA.
Anal Chem. 2018 May 15;90(10):5982-5988. doi: 10.1021/acs.analchem.7b04689. Epub 2018 May 2.PMID: 29688703 Free Article
Modulation of Phase Shift between Wnt and Notch Signaling Oscillations Controls Mesoderm Segmentation.
Sonnen KF, Lauschke VM, Uraji J, Falk HJ, Petersen Y, Funk MC, Beaupeux M, François P, Merten CA, Aulehla A.
Cell. 2018 Feb 22;172(5):1079-1090.e12. doi: 10.1016/j.cell.2018.01.026.PMID: 29474908 Free PMC Article
Single-Cell Droplet Microfluidic Screening for Antibodies Specifically Binding to Target Cells.
Shembekar N, Hu H, Eustace D, Merten CA.
Cell Rep. 2018 Feb 20;22(8):2206-2215. doi: 10.1016/j.celrep.2018.01.071.PMID: 29466744 Free PMC Article
Microfluidic single-cell technology in immunology and antibody screening.
Seah YFS, Hu H, Merten CA.
Mol Aspects Med. 2018 Feb;59:47-61. doi: 10.1016/j.mam.2017.09.004. Epub 2017 Sep 23. Review.PMID: 28927942 Free Article
Single-Virus Droplet Microfluidics for High-Throughput Screening of Neutralizing Epitopes on HIV Particles.
Chaipan C, Pryszlak A, Dean H, Poignard P, Benes V, Griffiths AD, Merten CA.
Cell Chem Biol. 2017 Jun 22;24(6):751-757.e3. doi: 10.1016/j.chembiol.2017.05.009. Epub 2017 May 25.PMID: 28552581 Free Article
Microfluidic train station: highly robust and multiplexable sorting of droplets on electric rails.
Frenzel D, Merten CA.
Lab Chip. 2017 Mar 14;17(6):1024-1030. doi: 10.1039/c6lc01544a.PMID: 28232987 Free PMC Article
Droplet-based microfluidics in drug discovery, transcriptomics and high-throughput molecular genetics.
Shembekar N, Chaipan C, Utharala R, Merten CA.
Lab Chip. 2016 Apr 21;16(8):1314-31. doi: 10.1039/c6lc00249h. Review.PMID: 27025767
Quantifying Preferences and Responsiveness of Marine Zooplankton to Changing Environmental Conditions using Microfluidics.
Ramanathan N, Simakov O, Merten CA, Arendt D.
PLoS One. 2015 Oct 30;10(10):e0140553. doi: 10.1371/journal.pone.0140553. eCollection 2015.PMID: 26517120 Free PMC Article
Efficient cell pairing in droplets using dual-color sorting.
Hu H, Eustace D, Merten CA.
Lab Chip. 2015 Oct 21;15(20):3989-93. doi: 10.1039/c5lc00686d. Epub 2015 Aug 27.PMID: 26313441
Dynein-Based Accumulation of Membranes Regulates Nuclear Expansion in Xenopus laevis Egg Extracts.
Hara Y, Merten CA.
Dev Cell. 2015 Jun 8;33(5):562-75. doi: 10.1016/j.devcel.2015.04.016. Epub 2015 May 21.PMID: 26004509 Free Article
Screening cellular metabolic activity.
El Debs B, Utharala R, Merten CA.
Nat Biotechnol. 2014 Nov;32(11):1092. doi: 10.1038/nbt.3058. No abstract available. PMID: 25380440
Fragmentation of DNA in a sub-microliter microfluidic sonication device.
Tseng Q, Lomonosov AM, Furlong EE, Merten CA.
Lab Chip. 2012 Nov 21;12(22):4677-82. doi: 10.1039/c2lc40595d.PMID: 23014736
Functional single-cell hybridoma screening using droplet-based microfluidics.
El Debs B, Utharala R, Balyasnikova IV, Griffiths AD, Merten CA.
Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):11570-5. doi: 10.1073/pnas.1204514109. Epub 2012 Jul 2.PMID: 22753519 Free PMC Article
Micro segmented-flow in biochemical and cell-based assays.
Clausell-Tormos J, Merten CA.
Front Biosci (Elite Ed). 2012 Jan 1;4:1768-79. Review.PMID: 22201992
A competitive co-cultivation assay for cancer drug specificity evaluation.
El Debs BW, Tschulena U, Griffiths AD, Merten CA.
J Biomol Screen. 2011 Sep;16(8):818-24. doi: 10.1177/1087057111414898. Epub 2011 Jul 25.PMID: 21788393
Microfluidic devices for diagnostic applications.
Eicher D, Merten CA.
Expert Rev Mol Diagn. 2011 Jun;11(5):505-19. doi: 10.1586/ERM.11.25. Review.PMID: 21707459
Retroviral display in gene therapy, protein engineering, and vaccine development.
Urban JH, Merten CA.
ACS Chem Biol. 2011 Jan 21;6(1):61-74. doi: 10.1021/cb100285n. Epub 2010 Dec 20. Review.PMID: 21171610