Tumour exosomal CEMIP protein promotes cancer cell colonization in brain metastasis

G. Rodrigues; A. Hoshino; C. M. Kenific; I. R. Matei; L. Steiner et al. 

Expression and differential regulation of human TERRA at several chromosome ends

M. Feretzaki; P. R. Nunes; J. Lingner 

Commentary on paper by Leroy C. Stevens (1960)

D. Duboule 

C/EBP alpha mediates the growth inhibitory effect of progestins on breast cancer cells

A. Silvina Nacht; R. Ferrari; R. Zaurin; V. Scabia; J. Carbonell-Caballero et al. 

The yeast C/D box snoRNA U14 adopts a “weak” K-turn like conformation recognized by the Snu13 core protein in solution

M-E. Chagot; M. Quinternet; B. Rothe; B. Charpentier; J. Coutant et al. 

CSL controls telomere maintenance and genome stability in human dermal fibroblasts

G. Bottoni; A. Katarkar; B. Tassone; S. Ghosh; A. Clocchiatti et al. 

Opposing chromatin remodelers control transcription initiation frequency and start site selection

S. Kubik; M. J. Bruzzone; D. Challal; R. Dreos; S. Mattarocci et al. 

A novel cell-based sensor detecting the activity of individual basic proprotein convertases

K. Loew; K. Hardes; C. Fedeli; N. G. Seidah; D. B. Constam et al. 

Impact of genome architecture on the functional activation and repression of Hox regulatory landscapes

E. Rodriguez-Carballo; L. Lopez-Delisle; N. Yakushiji-Kaminatsui; A. Ullate-Agote; D. Duboule 

Lymphoma Chemotherapy: Hungry Macrophages Strike the Final Blow

F. Duval; M. De Palma 

Live imaging screen reveals that TYRO3 and GAK ensure accurate spindle positioning in human cells

B. Wolf; C. Busso; P. Goenczy 

Expression of Prox1 in Medullary Thyroid Carcinoma Is Associated with Chromogranin A and Calcitonin Expression and with Ki67 Proliferative Index, but Not with Prognosis

C. Saglietti; S. La Rosa; G. P. Sykiotis; I. Letovanec; J-L. Bulliard et al. 

Integrin-Mediated Macrophage Adhesion Promotes Lymphovascular Dissemination in Breast Cancer

R. Evans; F. Flores-Borja; S. Nassiri; E. Miranda; K. Lawler et al. 

Targeted protein degradation through cytosolic delivery of monobody binders using bacterial toxins

N. E. Schmit; K. Neopane; O. Hantschel 

γ-Catenin-Dependent Signals Maintain BCR-ABL1+ B Cell Acute Lymphoblastic Leukemia

N. Luong-Gardiol; I. Siddiqui; I. Pizzitola; B. Jeevan-Raj; M. Charmoy et al. 

The phosphatase UBASH3B/Sts-1 is a negative regulator of Bcr-Abl kinase activity and leukemogenesis

A. A. Mian; I. Baumann; M. Liebermann; F. Grebien; G. Superti-Furga et al. 

Triggering of a Dll4–Notch1 loop impairs wound healing in diabetes

X. Zheng; S. Narayanan; V. G. Sunkari; S. Eliasson; I. R. Botusan et al. 

Macrophage interference on chemotherapy

M. De Palma; S. Nassiri; C. Cianciaruso 

Sequential Bone-Marrow Cell Delivery of VEGFA/S1P Improves Vascularization and Limits Adverse Cardiac Remodeling After Myocardial Infarction in Mice

M. M. Zak; P. Gkontra; C. Clemente; M. L. Squadrito; A. Ferrarini et al. 

Constrained Transcriptional Polarity In The Organization Of Mammalian Hox Gene Clusters

F. Darbellay; C. Bochaton; L. Lopez-Delisle; B. Mascrez; P. Tschopp et al. 

Aurora A er etic n reveals centrosome-independent polarization mechanism in Caenorhabditis elegans

K. Klinkert; N. Levernier; P. Gross; C. Gentili; L. von Tobel et al. 

An extended regulatory landscape drives Tbx18 activity in a variety of prostate-associated cell lineages

S. Negi; C. C. Bolt; H. Zhang; L. Stubbs 

Tail Bud Progenitor Activity Relies on a Network Comprising Gdf11, Lin28, and Hox13 Genes

R. Aires; L. de Lemos; A. Novoa; A. D. Jurberg; B. Mascrez et al. 

Two-Tier Mapper, an unbiased topology-based clustering method for enhanced global gene expression analysis

R. Jeitziner; M. Carrière; J. Rougemont; S. Oudot; K. Hess et al. 

Tissue- and sex-specific small RNAomes reveal sex differences in response to the environment

A. Bezler; F. Braukmann; S. M. West; A. Duplan; R. Conconi et al. 

Centriole assembly at a glance

P. Gönczy; G. Hatzopoulos 

Analysis of the S. pombe Meiotic Proteome Reveals a Switch from Anabolic to Catabolic Processes and Extensive Post-transcriptional Regulation

A. Krapp; R. Hamelin; F. Armand; D. Chiappe; L. Krapp et al. 

Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models

I. Keklikoglou; C. Cianciaruso; E. Güç; M. L. Squadrito; L. M. Spring et al. 

Direct targeting of NOTCH transcription complex by a novel small molecule CB-103 circumvents dose-limiting toxicities associated with pan-NOTCH inhibitors

R. Lehal; J. Zaric; M. Vigolo; C. Urech; M. Murone et al. 

Multicolor Single-Particle Reconstruction of Protein Complexes

C. Sieben; N. Banterle; K. M. Douglass; P. Gönczy; S. Manley 

Novel human cell line xenograft models of ER alpha-positive metastatic invasive lobular breast carcinoma as pre-clinical platforms for validating candidate genetic drivers

N. Tasdemir; J. Scott; J. Laotche; W. Hou; E. A. Bossart et al. 

Investigating cortactin as a genetic driver of disease progression in invasive lobular carcinoma

N. Tasdemir; M. J. Sikora; L. Zhu; K. M. Levine; J. Scott et al. 

Role of Activin-A signaling in melanoma

RADX: A novel single-stranded DNA-binding protein regulating telomere recombination

Hormone receptor signaling in estrogen receptor positive breast cancer

A Tale of Two Tumors: Unraveling the Complexities of Epigenetic Dysregulation in Cancer

Novel therapeutic strategies targeting the B-cell receptor signaling and antigen presentation pathways in non-Hodgkin lymphoma

Anti-angiogenic immunotherapy for lung cancer

Analysis of long-range gene regulation at the HoxD locus

Functional analysis of the telomeric long non-coding RNA TERRA

Adamts18 Function in Mammary Gland Development

Intraductal patient-derived xenografts of estrogen receptor α-positive breast cancer recapitulate the histopathological spectrum and metastatic potential of human lesions

M. Fiche; V. Scabia; P. Aouad; L. Battista; A. Treboux et al. 

Comparison of computational methods for the identification of topologically associating domains

M. Zufferey; D. Tavernari; E. Oricchio; G. Ciriello 

Short-lived AUF1 p42-binding mRNAs of RANKL and BCL6 have two distinct instability elements each

A. M. Dogar; R. Pauchard-Batschulat; B. Grisoni-Neupert; L. Richman; A. Paillusson et al. 

Oestrogen receptor alpha AF-1 and AF-2 domains have cell population-specific functions in the mammary epithelium

S. Cagnet; D. Ataca; G. Sflomos; P. Aouad; S. Schuepbach-Mallepell et al. 

Characterization of a B16-F10 melanoma model locally implanted into the ear pinnae of C57BL/6 mice

M. Potez; V. Trappetti; A. Bouchet; C. Fernandez-Palomo; E. Guc et al. 

Multiple roles of lymphatic vessels in peripheral lymph node development

E. Bovay; A. Sabine; B. Prat-Luri; S. Kim; K. Son et al. 

Improving Efficacy and Safety of Agonistic Anti-CD40 Antibody Through Extracellular Matrix Affinity

J. Ishihara; A. Ishihara; L. Potin; P. Hosseinchi; K. Fukunaga et al. 

Multicolor single-particle reconstruction of protein complexes

C. Sieben; N. Banterle; P. Gönczy; K. M. Douglass; S. Manley 

Heterogeneous combinatorial expression of Hoxd genes in single cells during limb development

P. J. Fabre; M. Leleu; B. Mascrez; Q. Lo Giudice; J. Cobb et al. 

Heterogeneous combinatorial expression of Hoxd genes in single cells during limb development

P. J. Fabre; M. Leleu; B. Mascrez; Q. Lo Giudice; J. Cobb et al. 

Trypanosoma brucei UMSBP2 is a single-stranded telomeric DNA binding protein essential for chromosome end protection

O. Klebanov-Akopyan; A. Mishra; G. Glousker; Y. Tzfati; J. Shlomai 

Snail mediates repression of the Dlk1-Dio3 locus in lung tumor-infiltrating immune cells

S. J. Groeneveld; J. Faget; N. Zangger; E. Meylan 

Detection and benchmarking of somatic mutations in cancer genomes using RNA-seq data

A. Coudray; A. M. Battenhouse; P. Bucher; V. R. Iyer 

Transformation-induced stress at telomeres is counteracted through changes in the telomeric proteome including SAMHD1

J. Majerska; M. Feretzaki; G. Glousker; J. Lingner 

PRDX1 and MTH1 cooperate to prevent ROS-mediated inhibition of telomerase

W. Ahmed; J. Lingner 

Notch2 Signaling Maintains NSC Quiescence in the Murine Ventricular-Subventricular Zone

A. Engler; C. Rolando; C. Giachino; I. Saotome; A. Erni et al. 

T cell–induced CSF1 promotes melanoma resistance to PD1 blockade

N. J. Neubert; M. Schmittnaegel; N. Bordry; S. Nassiri; N. Wald et al. 

Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation

T. M. Malta; A. Sokolov; A. J. Gentles; T. Burzykowski; L. Poisson et al. 

Bimodal CD40/Fas-Dependent Crosstalk between iNKT Cells and Tumor-Associated Macrophages Impairs Prostate Cancer Progression

F. Cortesi; G. Delfanti; A. Grilli; A. Calcinotto; F. Gorini et al. 

Periostin Limits Tumor Response to VEGFA Inhibition

I. Keklikoglou; E. Kadioglu; S. Bissinger; B. Langlois; A. Bellotti et al. 

PWMScan: a fast tool for scanning entire genomes with a position-specific weight matrix

G. Ambrosini; R. Groux; P. Bucher 

Remarks on the status of Fornasinius insignis ab. funereus Burgeon, 1937 (Coleoptera, Scarabaeidae, Cetoniinae, Goliathini)

M. De Palma 

Taxonomic revision of genus Fornasinius Bertoloni, 1853 with description of new taxa (Scarabaeidae: Cetoniinae)

M. De Palma 

Rapid activation of tumor-associated macrophages boosts preexisting tumor immunity

S. Hoves; C-H. Ooi; C. Wolter; H. Sade; S. Bissinger et al. 

EVIR: Chimeric receptors that enhance dendritic cell cross-dressing with tumor antigens

M. L. Squadrito; C. Cianciaruso; S. K. Hansen; M. De Palma 

ZYG-1 promotes limited centriole amplification in the C. elegans seam lineage

B. Wolf; F. Balestra; A. Spahr; P. Gönczy 

Vascular targeting of LIGHT normalizes blood vessels in primary brain cancer and induces intratumoural high endothelial venules

B. He; A. Jabouille; V. Steri; A. Johansson-Percival; I. Michael et al. 

Uncovering the balance of forces driving microtubule aster migration in C. elegans zygotes

A. De Simone; A. Spahr; C. Busso; P. Gönczy 

Ultrastructural diversity between centrioles of eukaryotes

A. Gupta; D. Kitagawa 

Tumor-Directed Blockade of CD47 with Bispecific Antibodies Induces Adaptive Antitumor Immunity

E. Dheilly; S. Majocchi; V. Moine; G. Didelot; L. Broyer et al. 

The Rise of the Cartwheel: Seeding the Centriole Organelle

P. Guichard; V. Hamel; P. Gönczy 

The ALK receptor in sympathetic neuron development and neuroblastoma

I. Janoueix-Lerosey; L. Lopez-Delisle; O. Delattre; H. Rohrer 

Tandem affinity purification of AtTERT reveals putative interaction partners of plant telomerase in vivo (vol 254, pg 1547, 2017)

J. Majerska; P. Schrumpfova; L. Dokladal; S. Schorova; K. Stejskal et al. 

Self-cleaning and wear-resistant polymer nanocomposite surfaces

P. Cully; F. Karasu; L. Muller; T. Jauzein; Y. Leterrier 

Role of Bicaudal C1 in renal gluconeogenesis and its novel interaction with the CTLH complex

L. Leal-Esteban; B. Rothe; S. Fortier; M. Isenschmid; D. Constam 

PI(4,5)P-2 forms dynamic cortical structures and directs actin distribution as well as polarity in Caenorhabditis elegans embryos

M. Scholze; K. Barbieux; A. De Simone; M. Boumasmoud; C. Suess et al. 

Pharmacological activity of CB-103: An oral pan-NOTCH inhibitor targeting the NOTCH transcription complex

D. Weber; R. Lehal; V. Frismantas; J. Bourquin; M. Bauer et al. 

Permeability and capillary effects in a channel-wise non-crimp fabric

D. Salvatori; B. Caglar; H. Teixido; V. Michaud 

Pan-SRC kinase inhibition blocks B-cell receptor oncogenic signaling in non-Hodgkin lymphoma

E. Battistello; N. Katanayeva; E. Dheilly; D. Tavernari; M. Donaldson et al. 

Noncoding copy-number variations are associated with congenital limb malformation

R. Flottmann; B. Kragesteen; S. Geuer; M. Socha; L. Allou et al. 

Membrane protein insertion through a mitochondrial beta-barrel gate

A. Hohr; C. Lindau; C. Wirth; J. Qiu; D. Stroud et al. 

Mannose receptor modulates macrophage polarization and allergic inflammation through miR-511-3p

Y. Zhou; D. Do; F. Ishmael; M. Squadrito; H. Tang et al. 

Interaction between the Caenorhabditis elegans centriolar protein SAS-5 and microtubules facilitates organelle assembly

S. Bianchi; K. Rogala; N. Dynes; M. Hilbert; S. Leidel et al. 

Integrated Microfluidic Device for Drug Studies of Early C. Elegans Embryogenesis

L. Dong; R. Jankele; M. Cornaglia; T. Lehnert; P. Gönczy et al. 

GKAP Acts as a Genetic Modulator of NMDAR Signaling to Govern Invasive Tumor Growth

L. Li; Q. Zeng; A. Bhutkar; J. Galvan; E. Karamitopoulou et al. 

Crystal Structure of Bicc1 SAM Polymer and Mapping of Interactions between the Ciliopathy-Associated Proteins Bicc1, ANKS3, and ANKS6

B. Rothe; C. Leettola; L. Leal-Esteban; D. Cascio; S. Fortier et al. 

Compartment-Specific Biosensors Reveal a Complementary Subcellular Distribution of Bioactive Furin and PC7

P. Ginefra; B. Filippi; P. Donovan; S. Bessonnard; D. Constam 

Cellular Endogenous NAD(P)H Fluorescence as a Label-Free Method for the Identification of Erythrocytes and Reticulocytes

L. Tauzin; V. Campos; M. Tichet 

Cellular Composition and Contribution of Tertiary Lymphoid Structures to Tumor Immune Infiltration and Modulation by Radiation Therapy

G. Boivin; P. Kalambaden; J. Faget; S. Rusakiewicz; P. Montay-Gruel et al. 

BioSITe: A Method for Direct Detection and Quantitation of Site-Specific Biotinylation

D. Kim; J. Cutler; C. Na; S. Reckel; S. Renuse et al. 

Stem cell-like memory CD8 T cells establish early in the acute response to Yellow Fever vaccination

M. S. A. Fuertes; A. Bovay; S. Nassiri; H. Maby-El Hajjami; H. Ouertatani et al. 

Investigating genetic drivers of disease progression in invasive lobular carcinoma

N. Tasdemir; M. Sikora; L. Zhu; K. Levine; A. Basudan et al. 

Characterization of cancer stem cell subpopulations from patient-derived xenografts of advanced prostate cancer

S. Karkampouna; M. De Menna; M. Germann; J. Grosjean; P. C. Gray et al. 

Characterization and profiling of CB-103, a novel small-molecule protein-protein interaction inhibitor targeting the NOTCH transcription complex

R. Lehal; C. Urech; M. Vigolo; M. Murone; F. Radtke 

CSCR and the identification of new molecular mineralocorticoid targets in retinal pigment epithelium cells

J. Canonica; T. Favez; L. Kowalczuk; Y. Arsenijevic; F. F. Behar-Cohen 

Neutrophils and Snail orchestrate the establishment of a protumor microenvironment in lung adenocarcinoma.

J. Faget; S. Groeneveld; G. Boivin; M. Sankar; N. Zangger et al. 

Glucose transporters in cancer – from tumor cells to the tumor microenvironment

P-B. Ancey; C. Contat; E. Meylan 

Consensus guidelines for the use and interpretation of angiogenesis assays

P. Nowak-Sliwinska; K. Alitalo; E. Allen; A. Anisimov; A. C. Aplin et al. 

When Telomerase Causes Telomere Loss

G. Glousker; J. Lingner